Dr. Alex Smithers is a physician at Advanced Rejuvenation in Sarasota, Florida, specialising in ultrasound-guided regenerative injection therapy. He is a Doctor of Oriental Medicine (D.O.M.) and a licensed Florida Acupuncture Physician (A.P.). He completed medical school and holds a Doctor of Medicine (M.D.) degree; he does not hold a Florida medical licence and practises under his Florida Acupuncture Physician licence. He received extensive postgraduate training in regenerative injection therapy through the American Association of Orthopaedic Medicine (AAOM), and is one of only a few doctors in Florida using Prolozone Therapy.
Ultrasound-guided injection uses real-time, high-definition ultrasound imaging to see the damaged tissue while the injection is being given. This does two things a blind injection cannot: it lets the physician confirm what is actually injured before treating it, and it places the needle precisely into the target structure. Dr. Smithers applies ultrasound guidance across his prolotherapy, PRP, and stem cell work, and is considered an expert among his peers in this approach.
Prolotherapy is a regenerative injection therapy in which an irritant solution is injected into damaged ligaments, tendons, or joints to provoke the body’s own repair response. It is used for chronic joint and soft-tissue pain that has not resolved with rest or physical therapy. At Advanced Rejuvenation, prolotherapy is performed under ultrasound guidance.
Prolozone is a regenerative injection therapy that combines nutrients and procaine with ozone gas, injected into damaged joints and soft tissue. Dr. Smithers is one of only a few physicians in Florida using Prolozone Therapy. Ozone therapy is also used systemically at the clinic.
Yes — for orthopedic and musculoskeletal conditions. Dr. Smithers performs platelet-rich plasma (PRP) and stem cell injections for joints, ligaments, and tendons, delivered under real-time ultrasound guidance for precise placement. PRP for facial, hair, and vaginal rejuvenation at Advanced Rejuvenation is performed by Dr. Kelly Schwemmer.
Dr. Smithers works with chronic musculoskeletal pain, joint injury, ligament and tendon damage, and prostate health. He also performs acupuncture, neural therapy — the injection of local anaesthetic into scars, trigger points, or autonomic ganglia — and acupoint injection therapy.
Regenerative injection therapy is generally considered for people with chronic joint or soft-tissue pain who want to avoid or delay surgery. It is not appropriate for every injury, and it is not a guaranteed alternative to surgical repair. The honest answer for any given patient depends on what the ultrasound shows — which is why the imaging comes first.
A native of Sarasota, Dr. Smithers’ family has a long history in the community.
Dr. Smithers sees patients at Advanced Rejuvenation, 1014 North East Avenue, Sarasota, FL 34237. Call (941) 330-8553 to book a consultation.
Also at Advanced Rejuvenation: Dr. John Lieurance (Functional Cranial Release, functional neurology, inner ear regeneration) and Dr. Kelly Schwemmer (hormone replacement therapy, sexual, vaginal, facial and hair rejuvenation).